Hydrochloric Acid → HCID 131711046, compound

Participants

Reaction Steps

A solution of 6 g. of the above product in 30 ml. of chloroform is treated with one equivalent of hydrochloric acid in ethanol to yield 5.6 g. of yellow solid; m.p. 224°-226°. A solution of this material in 110 ml. of hot methanol is concentrated to approximately half its volume, and then cooled overnight to yield 4.2 g. of yellow crystalline 2-[[4-[3-(dimethylamino)propoxy]phenyl]methylene]-2H-1,4-benzothiazin-3(4H)-one; hydrochloride (1:1); m.p. 224°-226°.

Provenance & Evidence