3-Methoxybenzaldehyde → HCID 20364865, compound

HRID 1679005Notes

Reaction equation

HRID 1679005 reaction equation
[CH2:1]([O:8][CH:9]([CH2:12][OH:13])[CH2:10][OH:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:14][O:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=1)[CH:19]=O>>[CH2:1]([O:8][CH:9]1[CH2:10][O:11][CH:19]([C:18]2[CH:21]=[CH:22][CH:23]=[C:16]([O:15][CH3:14])[CH:17]=2)[O:13][CH2:12]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 115693-MethoxybenzaldehydeHCID 2035672-(Phenylmethoxy)-1,3-propanediol

Product 1

HCID 20364865HCID 20364865, compoundYield 86.6%

Procedure

Using the method of Example 16, 2-benzyloxy-1,3-propane-diol (18.0 g, 0.1 mole), and 3-methoxybenzaldehyde (13.6 g, 0.1 mole) were reacted to give 26.0 g of oil which was distilled at 1 × 10-4 mm to give 20.2 g of product which distilled at a pot temperature of 200°-206° C. nmr analysis of this product indicated it to contain 37% cis-5-benzyloxy-2-(3-methoxyphenyl)-1,3-dioxane.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-efdea182f673491d8625bc55882de824
Source dataset
uspto-grants-1978_03
Patent number
US04077982

Reaction notes

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