2-(Phenylmethoxy)-1,3-propanediol → HCID 20364906, compound

HRID 1679017Notes

Reaction equation

HRID 1679017 reaction equation
[CH2:1]([O:3][CH:4]([O:14][CH2:15][CH3:16])[CH2:5][O:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)C.[CH2:17]([O:24]C(CO)CO)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:17]([O:24][CH:16]1[CH2:1][O:3][CH:4]([CH2:5][O:6][CH2:7][C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)[O:14][CH2:15]1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 2035672-(Phenylmethoxy)-1,3-propanediolHCID 4321487Benzyloxyacetaldehyde diethyl acetal

Product 1

HCID 20364906HCID 20364906, compound

Procedure

Using the procedure of Example 47, benzyloxyacetaldehyde diethyl acetal and 2-benzyloxy-1,3-propanediol were reacted to give 5-benzyloxy-2-benzyloxymethyl-1,3-dioxane, nD25 1.5438. The ir spectrum was consistent with the assigned structure. The nmr spectrum indicated 28% cis isomer and 72% trans isomer.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-0f9d7961629a4f7385a862e25d6cccfc
Source dataset
uspto-grants-1978_03
Patent number
US04077982

Reaction notes

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