Acetic Anhydride → HCID 86732955, compound

Participants

Reaction Steps

Acetic anhydride (1ml) was added to a solution of 1, 1 -di(4-biphenylyl)- 3 -amino-prop-1-ene (1g) in 99% formic acid (5ml) and the mixture was refluxed for 1 hour then poured onto ice. The solid was collected, washed with water, dried and then recrystallised from benzene/ n - propanol to furnish 1, 1-di (4 -biphenyly)-3-formamido-prop-1-ene (m.p. 171°- 173° C). This compound, reduced with lithium aluminium/hydride in ether/tetrahydrofuran at - 30° C, afforded 1, 1-di(4-biphenylyl)-3-methylamino-prop- 1-ene identical with that described in Example 4.

Provenance & Evidence