Dichloromethane → 1-[5'-(4-fluoro-benzoyl)-3,4,5,6,3',6'-hexahydro-2H,2'H-[1,4']bipyridinyl-1'-yl]-ethanone

HRID 167921Notes

Reaction equation

HRID 167921 reaction equation
[CH3:16][CH2:17][N:18]([CH2:19][CH3:20])[CH2:21][CH3:22].[Cl:33][CH2:34][Cl:35].[F:23][c:24]1[cH:25][cH:26][c:27]([C:28](=[O:29])[Cl:30])[cH:31][cH:32]1.[N:1]1([C:7]2=[CH:12][CH2:11][N:10]([C:13]([CH3:14])=[O:15])[CH2:9][CH2:8]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1>>[N:1]1([C:7]2=[C:12]([C:28]([c:27]3[cH:26][cH:25][c:24]([F:23])[cH:32][cH:31]3)=[O:29])[CH2:11][N:10]([C:13]([CH3:14])=[O:15])[CH2:9][CH2:8]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 678794-Fluorobenzoyl chlorideHCID 66616439HCID 66616439, compound

Product 1

HCID 666163811-[5'-(4-fluoro-benzoyl)-3,4,5,6,3',6'-hexahydro-2H,2'H-[1,4']bipyridinyl-1'-yl]-ethanone

Sources & evidence

ORD record
ord-4add2dc09ba949cb9bda9f76a4446b73
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…