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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1679302Generated: October 27, 2026

1-Chlorohexane → 1-Methyl-2-(5-aminomethylhexylisoxazol-3-yl)-5-nitroimidazole

https://huagongshe.com/reaction/1679302

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-ChlorohexaneHCID 10992—
Reactant1-Methyl-2-(5-methylhexylaminohexylisoxazol-3-yl)-5-nitroimidazoleHCID 70621776—
SolventDimethylformamideHCID 6228—
Product1-Methyl-2-(5-aminomethylhexylisoxazol-3-yl)-5-nitroimidazoleHCID 20362476—

Reaction Steps

The product prepared above is treated in a similar fashion with hexyl chloride in dimethylformamide for two hours. The recrystallized product is identified as 1-methyl-2-(5-methylhexylaminohexylisoxazol-3-yl)-5-nitroimidazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04080340
Source datasetuspto-grants-1978_03
ORD IDord-238700bc9a0d401a80f9c6e10a9b0ef2
Source noteuspto-grants-1978_03