3-Aminophenol → HCID 70620130, compound

HRID 1679313Notes

Reaction equation

HRID 1679313 reaction equation
[Br-].[O:2]=[C:3]1[N:8]([CH3:9])[C:7](=[O:10])[N:6]([CH3:11])[CH2:5][NH+:4]1[CH3:12].[NH2:13][C:14]1[CH:15]=[C:16]([OH:20])[CH:17]=[CH:18][CH:19]=1.C(=O)(O)[O-].[Na+]>O>[O:2]=[C:3]1[N:8]([CH3:9])[C:7](=[O:10])[N:6]([CH3:11])[CH:5]([C:17]2[CH:18]=[CH:19][C:14]([NH2:13])=[CH:15][C:16]=2[OH:20])[N:4]1[CH3:12]

Participants

5

Reactant 3

HCID 115683-AminophenolHCID 516892Sodium BicarbonateHCID 20362562HCID 20362562, compound

Product 1

HCID 70620130HCID 70620130, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

23.6 g (0.1 mol) of 2,4-dioxo-1,2,3,4-tetrahydro-1,3,5-trimethyl-s-triazinium bromide are dissolved in 50 ml of water and 10.9 g (0.1 mol) of m-aminophenol are added. After a few minutes, a clear solution has formed. 8 g of sodium bicarbonate are added to the solution. 25 g (89%) of 2,4-dioxo-hexahydro-1,3,5-trimethyl-6-[2-hydroxy-4-amino-phenyl]-s-triazine precipitate out as white crystals, which, after they have been dissolved in aqueous hydrochloric acid and the solution has been clarified with active charcoal and neutralised, melt at 240° C.

Workup

  1. waitAfter a few minutes
  2. customa clear solution has formed
  3. custom25 g (89%) of 2,4-dioxo-hexahydro-1,3,5-trimethyl-6-[2-hydroxy-4-amino-phenyl]-s-triazine precipitate out as white crystals, which
  4. dissolutionafter they have been dissolved in aqueous hydrochloric acid
  5. custommelt at 240° C.

Sources & evidence

ORD record
ord-514bfcec7c0c4961a2bf641854e4089b
Source dataset
uspto-grants-1978_03
Patent number
US04080379

Reaction notes

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