HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylene Glycol → HCID 178418543, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylene Glycol | HCID 174 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 3-Cyano-2-pyridone | HCID 577543 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178418543 | HCID 178418543 | — |
Reaction Steps
Prepare a solution containing 6 g of 3-cyano-2-pyridone, 7.5 g of potassium hydroxide pellets (85%), 8 ml. of ethylene glycol and 1.5 ml. of water. Heat the solution to 150°-160° C for 15 minutes and pour the reaction mixture into ice water. Acidify the aqueous solution to a pH of about 3. The 2-hydroxy-nicotinic acid precipitates, is collected by filtration and dried yielding the product of this step, m.p. 258°-260° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04081451 |
| Source dataset | uspto-grants-1978_03 |
| ORD ID | ord-5930d197e19a4385b5de2191007bfdc0 |
| Source note | uspto-grants-1978_03 |