Magnesium → HCID 178484159, compound

HRID 1679644Notes

Reaction equation

[Mg:1].[CH3:2][C@:3]1([OH:33])[C@@H:17]2[C:12](=[C:13]([OH:31])[C@:14]3([OH:30])[C:21](=[O:22])[C:20]([C:23]([NH2:25])=[O:24])=[C:19]([OH:26])[C@@H:18]([N:27]([CH3:29])[CH3:28])[C@@H:15]3[CH2:16]2)[C:10](=[O:11])[C:9]2[C:8]([OH:32])=[CH:7][CH:6]=[CH:5][C:4]1=2>>[Mg:1].[CH3:2][C@:3]1([OH:33])[C@@H:17]2[C:12](=[C:13]([OH:31])[C@:14]3([OH:30])[C:21](=[O:22])[C:20]([C:23]([NH2:25])=[O:24])=[C:19]([OH:26])[C@@H:18]([N:27]([CH3:29])[CH3:28])[C@@H:15]3[CH2:16]2)[C:10](=[O:11])[C:9]2[C:8]([OH:32])=[CH:7][CH:6]=[CH:5][C:4]1=2

Participants

Reactant 2

HCID 5462224Magnesium

HCID 178418840HCID 178418840, compound

Product 1

HCID 178484159HCID 178484159, compound

Procedure

Magnesium ions combine with tetracycline in solution to form magnesium-tetracycline chelates. Magnesium oxide is a convenient and preferred source of magnesium ions, but other magnesium compounds useful for the purpose of this invention include magnesium chloride, magnesium acetate and magnesium sulfate. The molar ratio of magnesium to tetracycline in these compositions is about from 0.8 to 1.3 mole. This ratio is advisable to produce clear stable solutions.

Sources & evidence

ORD record: ord-f59850fea1244b58a0342569b59690df
Source dataset: uspto-grants-1978_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04081528

Reaction notes

Loading…