HuagongsheHuagongshe Chemistry Print Report · For research reference only
Z-Ser(tBu)-Asn-Leu-OMe → H-Ser(tBu)-Asn-Leu-OMe
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Z-Ser(tBu)-Asn-Leu-OMe | HCID 131710201 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | H-Ser(tBu)-Asn-Leu-OMe | HCID 131710202 | — |
Reaction Steps
A solution of 6.3 g of Z-Ser(tBu)-Asn-Leu-OMe in 600 ml of methanol is hydrogenated in the presence of 1.2 g of palladium carbon (10% Pd). After 11/4 hours the catalyst is suctioned off and the filtrate evaporated to dryness at 30° C. bath temperature under vacuum. The resulting crystalline tripeptide derivative reveals in the thin-layer chromatogram on silica gel plates in chloroform+methanol (90:10) an Rf value of 0.11.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04271068 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-e3a52363a22e4b0282a264d09f5a4cd8 |
| Source note | uspto-grants-1981_06 |