HRID1679872

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10868

Dicyclohexylcarbodiimide

C13H22N2

HCID4064087

未命名化合物

结构：CCc1cn([C@H]2C[C@@](O)(C(C)=O)[C@@H](CO)O2)c(=O)[nH]c1=O

HCID54428309

未命名化合物

HCID86640756

未命名化合物

PRODUCTS

生成物

结构：CCc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)c(=O)[nH]c1=O

HCID6481845

未命名化合物

收率 62%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

A mixture of 0.3 g (0,001 mole) of 5-ethyl-3'-acetyl-2'-desoxyuridine, 1.2 g of dicyclohexylcarbodiimide and 2 ml of a pyridine solution of 0.002 mole of β-cyanoethyl phosphate were reacted to obtain 200 mg (62% yield) of 5-ethyl-2'-desoxyuridine-5'-monophosphate with an Rf=0.17 [1-7-2 ammonia-isopropanol-water mixture].

WORKUP

后处理

customwere reacted