HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → HCID 6481845, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | beta-Cyanoethyl phosphate | HCID 4064087 | — |
| Reactant | HCID 54428309 | HCID 54428309 | — |
| Reactant | HCID 86640756 | HCID 86640756 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 6481845 | HCID 6481845 | 62% |
Reaction Steps
A mixture of 0.3 g (0,001 mole) of 5-ethyl-3'-acetyl-2'-desoxyuridine, 1.2 g of dicyclohexylcarbodiimide and 2 ml of a pyridine solution of 0.002 mole of β-cyanoethyl phosphate were reacted to obtain 200 mg (62% yield) of 5-ethyl-2'-desoxyuridine-5'-monophosphate with an Rf=0.17 [1-7-2 ammonia-isopropanol-water mixture].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04271153 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-6222a14669f64033b20b62f2e3321a59 |
| Source note | uspto-grants-1981_06 |