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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1679893Generated: October 30, 2026

4-Amino-2-methylpyrimidine-5-carbaldehyde → HCID 12904730, compound

https://huagongshe.com/reaction/1679893

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-2-methylpyrimidine-5-carbaldehydeHCID 12904726—
Reactant2-(2-broMo-6-chlorophenyl)acetonitrileHCID 21850051—
ProductHCID 12904730HCID 12904730—

Reaction Steps

Following the procedure for Example 1, 2-bromo-6-chlorophenylacetonitrile is condensed with 4-amino-2-methylpyrimidin-5-carboxaldehyde to give 6-(2-bromo-6-chlorophenyl)-2-methylpyrido[2,3-d]-pyrimidin-7-amine, mp 272°-274° C., after recrystallization from acetonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04271164
Source datasetuspto-grants-1981_06
ORD IDord-dfa74eacda304a88a837dd211a33d75c
Source noteuspto-grants-1981_06