反应详情

Following the procedure of Example 1, 2-chloro-6-methylphenylacetonitrile is condensed with 4-amino-2-methylpyrimidine-5-carboxaldehyde to give 6-(2-chloro-6-methylphenyl)-2-methylpyrido[2,3-d]-pyrimidin-7-amine, mp 267°-271° C., after recrystallization from isopropanol.