p-Toluenesulfonic acid → HCID 86737760, compound

Participants

Reaction Steps

A mixture of 1.33 g (0.002 mole) of benzyl 1'-phenyl-6-tritylamino-spiro [penam-2,4'-piperidine]-3-carboxylate (obtained in 7.3) and 0.76 g of p-toluenesulfonic acid in 10 ml of acetone is stirred at ambient temperature for 6 hours. After filtering and drying, there is obtained 1.40 g of benzyl 6-amino-1'-phenyl-spiro[penam-2,4'-piperidine]-3-carboxylate di-p-toluenesulfonate. Yield: 92%; M.P. 168°-169° C. (decomposition).

Provenance & Evidence