Methanesulfonic Acid → HCID 12882189, compound

HRID 1680035Notes

Reaction equation

HRID 1680035 reaction equation
[CH3:1]/[C:2](=[CH:6]\[C:7]1[CH:12]=[CH:11][C:10]([CH2:13][C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)=[CH:9][CH:8]=1)/[C:3]([OH:5])=[O:4].[CH3:20][S:21]([OH:24])(=[O:23])=[O:22]>O>[S:21]([OH:24])(=[O:23])(=[O:22])[CH3:20].[CH3:1]/[C:2](=[CH:6]\[C:7]1[CH:12]=[CH:11][C:10]([CH2:13][C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)=[CH:9][CH:8]=1)/[C:3]([OH:5])=[O:4]

Participants

4

Reactant 2

HCID 6395Methanesulfonic AcidHCID 6437388(2E)-2-Methyl-3-[4-(3-pyridinylmethyl)phenyl]acrylic acid

Product 1

HCID 12882189HCID 12882189, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 96 mg of the acrylic acid(prepared as described in Example 15), 24.6 μl of methanesulphonic acid and one ml of water was concentrated under reduced pressure. The residue was dried in vacuo to give 97 mg of the title compound having the following physical characteristics:

Workup

  1. concentrationwas concentrated under reduced pressure
  2. customThe residue was dried in vacuo

Sources & evidence

ORD record
ord-6cd9d6052ed14316a4eb32a13721c230
Source dataset
uspto-grants-1981_06
Patent number
US04271170

Reaction notes

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