HuagongsheHuagongshe Chemistry Print Report · For research reference only
Z-Val-ONp → Z-Val-Thr-Leu-OtBu
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Z-Val-ONp | HCID 112124 | — |
| Reactant | H-Thr-Leu-OtBu | HCID 131712120 | — |
| Reactant | H-Thr-D-Leu-OtBu | HCID 131712254 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Z-Val-Thr-Leu-OtBu | HCID 131712119 | 72% |
Reaction Steps
Coupling of 7.85 g Z-Val-ONp with 5.53 g H-Thr-Leu-OtBu in 160 ml DMF in the way described in C (2) provides Z-Val-Thr-Leu-OtBu in 72% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04271152 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-7fea017de74248d892c145bf1625bb1e |
| Source note | uspto-grants-1981_06 |