HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → Eltenac
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | HCID 70573760 | HCID 70573760 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Eltenac | HCID 51717 | — |
Reaction Steps
357 mg (1 mmole) of 4-(2,6-dichloroanilino)-3-thiophenacetic acid tert.-butyl ester are heated to the boil with 10 mg of p-toluenesulfonic acid in toluene for 2 hours. The reaction solution is washed with water, dried and concentrated to give 4-(2,6-dichloroanilino)-3-thiophenacetic acid (m. 179° to 180°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04272507 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-4c2d593767e94b969a86ec101f64e595 |
| Source note | uspto-grants-1981_06 |