反应详情

357 mg (1 mmole) of 4-(2,6-dichloroanilino)-3-thiophenacetic acid tert.-butyl ester are heated to the boil with 10 mg of p-toluenesulfonic acid in toluene for 2 hours. The reaction solution is washed with water, dried and concentrated to give 4-(2,6-dichloroanilino)-3-thiophenacetic acid (m. 179° to 180°).

1. washThe reaction solution is washed with water
2. customdried
3. concentrationconcentrated