Sulfuric Acid → HCID 23457236, compound

HRID 1680168Notes

Reaction equation

HRID 1680168 reaction equation
[Cl:1][C:2]1[CH:16]=[CH:15][CH:14]=[C:13]([Cl:17])[C:3]=1[NH:4][C:5]1[C:6]([CH2:10][C:11]#[N:12])=[CH:7][S:8][CH:9]=1.S(=O)(=O)(O)[OH:19]>>[Cl:1][C:2]1[CH:16]=[CH:15][CH:14]=[C:13]([Cl:17])[C:3]=1[NH:4][C:5]1[C:6]([CH2:10][C:11]([NH2:12])=[O:19])=[CH:7][S:8][CH:9]=1

Participants

3

Reactant 2

HCID 1118Sulfuric AcidHCID 23457191HCID 23457191, compound

Product 1

HCID 23457236HCID 23457236, compound

Procedure

28.3 g (0.1 mole) of 4-(2,6-dichloroanilino)-3-thiophenacetonitrile are introduced into 150 ml of concentrated sulfuric acid and stirred for one hour at room temperature. It is poured onto ice, and the precipitate which has formed is filtered off. Recrystallization from ethyl acetate yields 4-(2,6-dichloroanilino)-3-thiophenacetamide (m. 172° to 173°).

Workup

  1. additionIt is poured onto ice
  2. customthe precipitate which has formed
  3. filtrationis filtered off
  4. customRecrystallization from ethyl acetate

Sources & evidence

ORD record
ord-b9379a39fe8b4647abdcb1855130d5cb
Source dataset
uspto-grants-1981_06
Patent number
US04272507

Reaction notes

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