HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → N-Trifluoroacetyl-2-aminoethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | Ethylthiol trifluoroacetate | HCID 67844 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-Trifluoroacetyl-2-aminoethanol | HCID 95211 | — |
Reaction Steps
Ethanolamine (12 g) is dissolved in methanol (50 ml) and S-ethylthiotrifluoroacetate (35 g) is added dropwise. The reaction is permitted to stand overnight irrigated with a stream of argon to remove ethanethiol. The excess solvent is removed in vacuo to leave the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04272525 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-081d54460a784969b6ff6bd41a780154 |
| Source note | uspto-grants-1981_06 |