HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → HCID 86737791, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | N-Hydroxysuccinimide | HCID 80170 | — |
| Reactant | N-(trifluoroacetyl)aminoacetic acid | HCID 136227 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86737791 | HCID 86737791 | — |
Reaction Steps
N-Trifluoroacetylglycine (684 mg) and N-hydroxysuccinimide (480 mg) in 5 ml of dry CH2Cl2 at 50° C. are treated with a solution of 915 mg dicyclohexylcarbodiimide (4.43 mmol) in 5 ml of CH2Cl2. The mixture is stirred at room temperature overnight, is then filtered and evaporated to produce the named compound which can be used in subsequent reactions without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04272525 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-64750fedbb2743c6ae1227b0ee8ea70e |
| Source note | uspto-grants-1981_06 |