HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 168027Generated: October 31, 2026
Hydrochloric Acid → 1-[3-(8-Hydroxy-6-azaspiro[2.5]octan-6-yl)propyl]-3-methyl-4-[3-(trifluoromethoxy)phenyl]piperazin-2-one
https://huagongshe.com/reaction/168027
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Borane | HCID 6331 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 6-Azaspiro[2.5]octan-4-ol | HCID 66782700 | — |
| Reactant | 3-[3-Methyl-2-oxo-4-(3-trifluoromethoxy-phenyl)-piperazin-1-yl]-propionaldehyde | HCID 86638391 | — |
| Product | 1-[3-(8-Hydroxy-6-azaspiro[2.5]octan-6-yl)propyl]-3-methyl-4-[3-(trifluoromethoxy)phenyl]piperazin-2-one | HCID 66782987 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
|---|
| ORD ID | ord-fce04749b4b54766adb17b60967ae543 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
|---|
