Sulfuric Acid → 4-Hydroxybenzaldehyde

HRID 1680555Notes

Reaction equation

N[C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.S(=O)(=O)(O)[OH:11]>>[OH:11][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 1118Sulfuric Acid

HCID 111584-Aminobenzaldehyde

Product 1

HCID 1264-Hydroxybenzaldehyde

Procedure

The procedure of Example 8 was followed except that the reaction of p-aminobenzaldehyde with sulphuric acid in 40% aqueous solution was effected at 120° C. for 15 minutes, to obtain 2.6 g (0.021 mol) of p-hydroxybenzaldehyde, accompanied with formation of tarry materials in large quantities. The yield of p-hydroxybenzaldehyde so obtained was 53%, based on the weight of p-aminobenzaldehyde used.

Sources & evidence

ORD record: ord-4edc9c0375ee418aa1a9801b0145fdb7
Source dataset: uspto-grants-1981_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04273941

Reaction notes

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