Acetone → HCID 23455318, compound

HRID 1680633Notes

Reaction equation

HRID 1680633 reaction equation
CC(C)=O.[Cl:5][C:6]1[CH:7]=[CH:8][C:9]2[S:13][C:12]([SH:14])=[N:11][C:10]=2[CH:15]=1.[Br:16][CH:17]([C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[CH:23][CH:22]=1)[C:18](O)=O.C(OC(=O)C)(=O)C>C(O)(=O)C>[Br-:16].[Cl:5][C:6]1[CH:7]=[CH:8][C:9]2[S:13][C:12]3[S:14][C:17]([C:21]4[CH:26]=[CH:25][C:24]([Cl:27])=[CH:23][CH:22]=4)=[CH:18][N+:11]=3[C:10]=2[CH:15]=1

Participants

6

Reactant 4

HCID 180AcetoneHCID 7918Acetic AnhydrideHCID 10490868alpha-Bromo-4-chlorophenylacetic acidHCID 178527796HCID 178527796, compound

Product 1

HCID 23455318HCID 23455318, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

An acetone solution of 10.0 g (0.05 moles) 5-chloro-2-mercaptobenzothiazole and 12.5 g. (0.01 moles) α-bromo-(p-chloro)phenylacetic acid containing 50 ml. glacial acetic acid and 20 ml. acetic anhydride is heated in an open flask. When the solution is concentrated to a small volume, the precipitated solid, weighing 15.1 g. (70% yield) is collected.

Workup

  1. concentrationWhen the solution is concentrated to a small volume
  2. custom(70% yield) is collected

Sources & evidence

ORD record
ord-725b6700d45a4eba85fce3ce92551c0c
Source dataset
uspto-grants-1981_06
Patent number
US04275065

Reaction notes

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