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A mixture of 4.0 g (0.016 mole) of 4-amino-2-(phenoxymethyl)pteridine and 400 ml of 5% aqueous sodium hydroxide is brought slowly to 95° C. and maintained at this temperature for 2 hours. After cooling, the solution obtained is acidified with acetic acid to pH 5.5. The precipitate formed is isolated by filtration. It is purified by recrystallization from ethanol. Yld: 2.8 g (70%), m.p. 220°-221° C.

1. customis brought slowly to 95° C.
2. temperaturemaintained at this temperature for 2 hours
3. temperatureAfter cooling
4. customthe solution obtained
5. customThe precipitate formed
6. customis isolated by filtration
7. customIt is purified by recrystallization from ethanol