Potassium Hydroxide → HCID 15714341, compound

Participants

Reaction Steps

410 mg (7.3.10-3 mol) of potassium hydroxide are added under an inert atmosphere to a suspension of 1 g (5.7.10-3 mol) of 5-hydroxy-4-methyl-2H-1-benzopyran-2-one in 10 ml of water and 10 ml of acetone. After 10 minutes at room temperature, 770 mg (6.2.10-3 mol) of dimethylthiocarbamoyl chloride in 10 ml of acetone are added at 0° C. The reaction mixture is stirred for 2 hours at room temperature and then, after evaporation of the acetone, the expected derivative is precipitated in water to give 1.35 g (yield: 90%) of the expected product.

Provenance & Evidence