HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 14425093, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | 3-Methoxy-3-oxo-2-[(thiophen-2-yl)methyl]propanoate | HCID 19807162 | — |
| Product | HCID 14425093 | HCID 14425093 | 75.4% |
Reaction Steps
11.8 g of monomethyl 2-thienylmethylmalonate, 5.8 ml of diethylamine and 5.0 ml of 36% aqueous formaldehyde solution are stirred under argon at R.T. for 1 h. The water is subsequently removed in vacuo, and the residue is chromatographed. 7.6 g of the title compound are obtained as a colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05169841 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-7abc50ab21a3441bb96b2f9370d01135 |
| Source note | uspto-grants-1992_12 |