Acetic Anhydride → HCID 13901908, compound

HRID 1681153Notes

Reaction equation

HRID 1681153 reaction equation
[CH2:1]1[C:13]2[NH:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH2:4][CH2:3][NH:2]1.[C:14](OC(=O)C)(=[O:16])[CH3:15]>C(OCC)(=O)C.N1C=CC=CC=1>[C:14]([N:2]1[CH2:3][CH2:4][C:5]2[C:6]3[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=3)[NH:12][C:13]=2[CH2:1]1)(=[O:16])[CH3:15]

Participants

5

Reactant 2

HCID 7918Acetic AnhydrideHCID 107838Tetrahydro-beta-carboline

Product 1

HCID 13901908HCID 13901908, compound

Reagents, catalysts & solvents 2

HCID 1049PyridineSolventHCID 8857Ethyl AcetateSolvent

Procedure

2-acetyl-1,2,3,4-tetrahydro-β-carboline was prepared as follows: 1 g of 1,2,3,4-tetrahydro-β-carboline (Sigma) was dissolved in a minimum of ethyl acetate, and pyridine 3 mL) was added along with acetic anhydride (1.5 mL). After 30 minutes, the mixture was dried and the resulting 2-acetyl-1,2,3,4-tetrahydro-β-carboline was recrystallized from acetone.

Workup

  1. customthe mixture was dried
  2. customthe resulting 2-acetyl-1,2,3,4-tetrahydro-β-carboline was recrystallized from acetone

Sources & evidence

ORD record
ord-2486ad43492a437c97c2382aae4b6e0a
Source dataset
uspto-grants-1992_12
Patent number
US05169852

Reaction notes

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