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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1681157Generated: November 4, 2026

Benzaldehyde → 5,5-Dimethyl-2-phenyl-1,3-thiazolidine-4-carboxylic acid

https://huagongshe.com/reaction/1681157

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantL-PenicillamineHCID 92863—
SolventEthanolHCID 702—
SolventWaterHCID 962—
Product5,5-Dimethyl-2-phenyl-1,3-thiazolidine-4-carboxylic acidHCID 41947—

Reaction Steps

One mole of benzaldehyde was dissolved in 100 cc of 90% ethanol with continuous stirring. One mole of penicillamine was dissolved in water with continuous stirring. The two solutions were then mixed together while stirring was continued. The solution was left to stand at room temperature. Within 15 minutes, a white precipitate occurred. The white precipitate was washed with distilled water through sintered glass. The washed precipitate was then dryed at 100° C. to obtain crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05169858
Source datasetuspto-grants-1992_12
ORD IDord-b4e6c42e1d1f492cb240c1c87439436c
Source noteuspto-grants-1992_12