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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1681180Generated: November 3, 2026

4-Fluorobenzyl bromide → 1-Benzyl-3-(4'-fluorobenzyloxymethyl) piperidine

https://huagongshe.com/reaction/1681180

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzyl bromideHCID 68021—
Reactant(1-Benzylpiperidin-3-yl)methanolHCID 10398044—
Product1-Benzyl-3-(4'-fluorobenzyloxymethyl) piperidineHCID 54262733—

Reaction Steps

Following the procedure for Example 139, 4-fluorobenzylbromide and 1-benzyl-3-(hydroxy-methyl)piperidine were reacted to give 1-benzyl-3-(4'-fluorobenzyloxymethyl) piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05169855
Source datasetuspto-grants-1992_12
ORD IDord-26edd8d4c30f4c9b8c061bc97d87c5f2
Source noteuspto-grants-1992_12