Salicylaldehyde → HCID 136403409, compound

Participants

Reaction Steps

2.5 ml of 1N sodium hydroxide solution and 305 mg (2.5 mmol) of salicylaldehyde are added to a solution of 488 mg (2.5 mmol) of N-(3-aminoxy-2-fluoropropyl)-methylamine dihydrochloride in 10 ml of ethanol and the mixture is stirred for 24 hours at room temperature. The reaction mixture is then concentrated to dryness by evaporation and the residue is crystallised from ethanol/ether.

Provenance & Evidence