Hydrochloric Acid → HCID 19807613, compound

HRID 1681291Notes

Reaction equation

HRID 1681291 reaction equation
Cl[C:2]1[C:3](=[O:22])[C:4](=[O:21])[C:5]=1[C:6]1[CH:7]=[C:8]([CH3:20])[C:9]2[C:15]=1[C:14]([CH3:16])=[CH:13][CH:12]=[C:11]([CH:17]([CH3:19])[CH3:18])[CH:10]=2.[OH2:23].Cl>O1CCOCC1>[OH:23][C:2]1[C:3](=[O:22])[C:4](=[O:21])[C:5]=1[C:6]1[CH:7]=[C:8]([CH3:20])[C:9]2[C:15]=1[C:14]([CH3:16])=[CH:13][CH:12]=[C:11]([CH:17]([CH3:19])[CH3:18])[CH:10]=2

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 19807614HCID 19807614, compound

Product 1

HCID 19807613HCID 19807613, compoundYield 62%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

62.4 g (0.2 mol) of 3-chloro-4-(7-isopropyl-1,4-dimethyl-3-azulenyl)cyclobut-3-ene-1,2-dione were refluxed in 200 ml of dioxane, 40 ml of water and 2 ml of concentrated hydrochloric acid for 8 hours. The solvent was removed under reduced pressure, and the remaining oily residue was crystallized by adding dichloromethane. 36.5 g (62%) of 3-hydroxy-4-(7-isopropyl-1,4-dimethyl-3-azulenyl)cyclobut-3-ene-1,2-dione were obtained as dark brown crystals of melting point 120°-123° C. The substance was used without further purification for synthesizing dyes.

Workup

  1. customThe solvent was removed under reduced pressure
  2. customthe remaining oily residue was crystallized
  3. additionby adding dichloromethane

Sources & evidence

ORD record
ord-984c11e340c94100b245b60bd27ecf84
Source dataset
uspto-grants-1992_12
Patent number
US05169975

Reaction notes

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