HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → Benzoic acid, 4-(phenylmethoxy)-, 1-(trifluoromethyl)heptyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Dimethylaminopyridine | HCID 21885 | — |
| Reactant | 2-Octanol, 1,1,1-trifluoro- | HCID 97804 | — |
| Reactant | 4-Benzyloxybenzoylchloride | HCID 3766410 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Benzoic acid, 4-(phenylmethoxy)-, 1-(trifluoromethyl)heptyl ester | HCID 14549213 | — |
Reaction Steps
4-Benzyloxy-benzoic acid chloride in an amount of 4.3 g was dissolved in 50 ml of methylene chloride, to which a solution of 2.9 g of optically active 1,1,1-trifluoro-2-octanol, 0.6 g of dimethylaminopyridine and 1.7 g of triethylamine in 50 ml of methlene chloride was gradually added under cooling with ice.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05171471 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-941b1beda29e4e81b66d34d17358aef7 |
| Source note | uspto-grants-1992_12 |