m-Chloroperbenzoic acid → HCID 178464590, compound

HRID 1681335Notes

Reaction equation

HRID 1681335 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:9][C:8]([S:10][CH2:11][CH2:12][NH:13][C:14]([NH:18][C:19]#[N:20])=[N:15][CH2:16][CH3:17])=[N:7][C:6]=2[CH:21]=1.ClC1C=CC=C(C(OO)=[O:30])C=1>C(Cl)Cl>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:9][C:8]([S:10]([CH2:11][CH2:12][NH:13][C:14]([NH:18][C:19]#[N:20])=[N:15][CH2:16][CH3:17])=[O:30])=[N:7][C:6]=2[CH:21]=1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 178464585HCID 178464585, compound

Product 1

HCID 178464590HCID 178464590, compoundYield 95.3%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Dissolved in 8 ml of methylene chloride were 0.20 g (0.59 mmol) of the compound obtained in Example 27, and 0.15 g (0.59 mmol) of m-chloroperbenzoic acid with a 70% purity were added to the solution, which was stirred at room temperature for 2 hours. The solvent was removed in vacuo and the residue was purified by silica gel chromatography to obtain 0.20 g of white crystalline powders (95% yield).

Workup

  1. additionwere added to the solution, which
  2. customThe solvent was removed in vacuo
  3. customthe residue was purified by silica gel chromatography

Sources & evidence

ORD record
ord-c536671b13f84bb6b5fcfa3fbcb0d922
Source dataset
uspto-grants-1992_12
Patent number
US05171746

Reaction notes

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