Sodium ion → 5-(Benzimidazol-2-yl)-3-(1-Methylpiperidin-4-yl)-1H-Indole

HRID 168136Notes

Reaction equation

HRID 168136 reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][nH:10][c:11]3[cH:12][cH:13][c:14]([B:17]([OH:18])[OH:19])[cH:15][c:16]23)[CH2:6][CH2:7]1.[Cl:20][c:21]1[nH:22][c:23]2[c:24]([n:25]1)[cH:26][cH:27][cH:28][cH:29]2.[Na+:30].[Na+:31].[O-:32][C:33](=[O:34])[O-:35].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[CH3:1][N:2]1[CH2:3][CH2:4][CH:5]([c:8]2[cH:9][nH:10][c:11]3[cH:12][cH:13][c:14](-[c:21]4[n:22][c:23]5[c:24]([nH:25]4)[cH:26][cH:27][cH:28][cH:29]5)[cH:15][c:16]23)[CH2:6][CH2:7]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 8028TetrahydrofuranHCID 19660Carbonate IonHCID 785722-ChlorobenzimidazoleHCID 120418133-(1-Methylpiperidin-4-yl)-1H-Indole-5-Boronic Acid

Product 1

HCID 120432585-(Benzimidazol-2-yl)-3-(1-Methylpiperidin-4-yl)-1H-Indole

Sources & evidence

ORD record
ord-66d780122e804779b08498c57dc4ebbb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…