HCID 19806576, compound → HCID 19806593, compound

HRID 1681386Notes

Reaction equation

HRID 1681386 reaction equation
[CH3:1][C:2]1[N:3]([C:7]2[CH:8]=[CH:9][C:10]([N+:15]([O-])=O)=[C:11]([CH:14]=2)[CH2:12][OH:13])[CH:4]=[CH:5][N:6]=1>[Pd].CO>[NH2:15][C:10]1[CH:9]=[CH:8][C:7]([N:3]2[CH:4]=[CH:5][N:6]=[C:2]2[CH3:1])=[CH:14][C:11]=1[CH2:12][OH:13]

Participants

4

Reactant 1

HCID 19806576HCID 19806576, compound

Product 1

HCID 19806593HCID 19806593, compoundYield 100%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of 5-(2-methylimidazol-1-yl)-2-nitrobenzylalcohol (308 mg), 10% Pd/C(84 mg) and methanol (5.0 ml) was hydrogenated at 1 atmosphere. The mixture was stirred at room temperature for 2 hours and filtered to remove the catalyst. The filtrate was diltilled under reduced pressure to give 268 mg (100%) of the title compound.

Workup

  1. filtrationfiltered
  2. customto remove the catalyst

Sources & evidence

ORD record
ord-7c3c9ab6955744e8ae1ca2d7653bb27f
Source dataset
uspto-grants-1992_12
Patent number
US05171851

Reaction notes

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