Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methylimidazole | HCID 12749 | — |
| Reactant | 3-(4-Fluorobenzoyl)propyl chloride | HCID 19750 | — |
| Product | HCID 13764020 | HCID 13764020 | — |
Reaction Steps
50 g (0.25 mol) of 4-chloro-4'-fluorobutyrophenone are combined with 130 g (1.58 mol) of 2-methylimidazole and heated to 200° C. under nitrogen for 18 hr. Crystallization from ethyl acetate provides the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05171858 |
|---|
| Source dataset | uspto-grants-1992_12 |
|---|
| ORD ID | ord-eb1a3f8505674f118da69911212c6b5f |
|---|
| Source note | uspto-grants-1992_12 |
|---|
