HCID 13764026, compound → HCID 13764034, compound

HRID 1681405Notes

Reaction equation

HRID 1681405 reaction equation
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[C:11]3[N:12]([C:16]([CH3:19])=[N:17][CH:18]=3)[CH2:13][CH2:14][CH:15]=2)=[CH:6][CH:5]=1)[CH3:2]>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[CH2:1]([O:3][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[C:11]3[N:12]([C:16]([CH3:19])=[N:17][CH:18]=3)[CH:13]=[CH:14][CH:15]=2)=[CH:8][CH:9]=1)[CH3:2]

Participants

4

Reactant 1

HCID 13764026HCID 13764026, compound

Product 1

HCID 13764034HCID 13764034, compound

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 6344DichloromethaneSolvent

Procedure

Combine 15 g (59 mmol) of the product of Example IV with 150 g of manganese dioxide in 500 ml of methylene chloride and heat at reflux for 24 hr. Filter off the solids and remove the solvents under vacuum. Crystallize the residue from ethyl acetate to provide the title compound.

Workup

  1. temperatureat reflux for 24 hr
  2. filtrationFilter off the solids
  3. customremove the solvents under vacuum
  4. customCrystallize the residue from ethyl acetate

Sources & evidence

ORD record
ord-a54e52d530d044ba9c45640b3ba5f9be
Source dataset
uspto-grants-1992_12
Patent number
US05171858

Reaction notes

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