Benzenemethanesulfonamide → Methyl oxo[(phenylmethanesulfonyl)amino]acetate

HRID 1681477Notes

Reaction equation

HRID 1681477 reaction equation
[CH2:1]([S:8]([NH2:11])(=[O:10])=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:12][O:13][C:14]([C:16](Cl)=[O:17])=[O:15]>>[CH2:1]([S:8]([NH:11][C:16](=[O:17])[C:14]([O:13][CH3:12])=[O:15])(=[O:10])=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 78318BenzenemethanesulfonamideHCID 79846Methyl chloroglyoxylate

Product 1

HCID 13186355Methyl oxo[(phenylmethanesulfonyl)amino]acetate

Procedure

A mixture of benzylsulfonamide (16.7 g, 0.0975 mole) and methyloxalylchloride (38 ml, 0.41 mol) was heated at 100°-120° C. for 2 hours. Upon evaporation, there was obtained the title compound, 20.6 g, mp 119°-124° C.

Workup

  1. temperaturewas heated at 100°-120° C. for 2 hours
  2. customUpon evaporation

Sources & evidence

ORD record
ord-90eb4b80eff44321871539d18c42fae0
Source dataset
uspto-grants-1992_12
Patent number
US05171860

Reaction notes

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