5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine → HCID 19806671, compound

Participants

Reaction Steps

To a solution of 2-[(5-dimethylaminomethyl-2furanyl)methylthio]ethylamine (440 mg, 2 mmol) in acetonitrile (6 ml) there was added 3-ethoxy-4-amino-5-methylsulfonylisothiazole-1-oxide (480 mg, 2 mmol). This mixture was stirred under a nitrogen atmosphere for 15 hours as product slowly crystallized out. Precipitate was collected by filtration, washed with acetonitrile, diethyl ether and air dried to give 650 mg, of title compound, mp 134°-137°.

Provenance & Evidence