Thionyl Chloride → HCID 19762694, compound

HRID 1681570Notes

Reaction equation

HRID 1681570 reaction equation
[CH3:1][C:2]1([C:8]2[CH:9]=[C:10]([CH:14]=[CH:15][C:16]=2[O:17][CH3:18])[C:11](O)=[O:12])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.S(Cl)([Cl:21])=O>>[CH3:1][C:2]1([C:8]2[CH:9]=[C:10]([CH:14]=[CH:15][C:16]=2[O:17][CH3:18])[C:11]([Cl:21])=[O:12])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 18371174HCID 18371174, compound

Product 1

HCID 19762694HCID 19762694, compoundYield 100%

Procedure

1.24 g (5 mmoles) of 3-(1-methylcyclohexyl)-4-methoxybenzoic acid and 15 ml of thionyl chloride are heated at reflux until the cessation of gas evolution. The reaction mixture is evaporated to dryness. 1.32 g (100% yield) of crude 3-(1-methylcyclohexyl)-4-methoxybenzoic acid chloride which is used as such for the following synthesis are obtained.

Workup

  1. temperatureat reflux until the cessation of gas evolution
  2. customThe reaction mixture is evaporated to dryness

Sources & evidence

ORD record
ord-4e7f54a7c9e3402b923644cda1740b25
Source dataset
uspto-grants-1992_12
Patent number
US05173289

Reaction notes

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