HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19382157, compound → 3-Aminomethyl-1-benzyl-3-methoxy-pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19382157 | HCID 19382157 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Aminomethyl-1-benzyl-3-methoxy-pyrrolidine | HCID 53745740 | — |
Reaction Steps
The solution of 26.5 g (0.11 mol, 93% proof) 1-benzyl-3-cyano-3-methoxypyrrolidine in 300 ml methanol is hydrogenated at 15 g Raney-Ni at 60° C./100 bar H2. The catalyst is removed by filtration, the methanol is removed in vacuo, and the residue is distilled.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05173484 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-2757cbe2495943eaa2ba27d3eba53ede |
| Source note | uspto-grants-1992_12 |