Hydrazine hydrate (1:1) → HCID 19805407, compound

HRID 1681633Notes

Reaction equation

HRID 1681633 reaction equation
O.[NH2:2][NH2:3].[CH2:4]([N:11]1[C:19]2[N:18]=[CH:17][N:16]([CH3:20])[C:15]=2[C:14](SC)=[N:13][C:12]1=[O:23])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>O>[CH2:4]([N:11]1[C:19]2[N:18]=[CH:17][N:16]([CH3:20])[C:15]=2[C:14]([NH:2][NH2:3])=[N:13][C:12]1=[O:23])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 19735594HCID 19735594, compound

Product 1

HCID 19805407HCID 19805407, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

After 16.0 ml of hydrazine hydrate was added to 2.00 g (6.99 mmol) of Compound h prepared in Reference Example 8, the mixture was stirred at room temperature for day and night. The reaction mixture was poured onto 300 ml of water and the precipitates were taken out by filtration and washed with ether to give 1.60 g (yield, 85%) of Compound p as a white powder.

Workup

  1. customprepared in Reference Example 8
  2. filtrationthe precipitates were taken out by filtration
  3. washwashed with ether
  4. customto give

Sources & evidence

ORD record
ord-54f5903d29814782816448bb78711e2c
Source dataset
uspto-grants-1992_12
Patent number
US05173492

Reaction notes

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