Sodium Hydroxide → HCID 66653131, compound

Participants

Reaction Steps

A suspension of 19.5 g of the above hydrochloride in 300 ml of water was basified to pH 14 with sodium hydroxide solution. The mixture was stirred for 10 minutes, filtered and the filtrate extracted with three 100 ml portions of dichloromethane. The extracts were combined, washed with brine, dried, filtered and evaporated to dryness, giving 14.5 g of the desired compound as the free base.

Provenance & Evidence