HRID1681682

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：[Mg+2].[Mg+2].[O-][Si]([O-])([O-])[O-]

HCID66225

Magnesium orthosilicate

Mg2O4Si

$结构：CCCCCCCC/C=C\CCCCCCCC(O)CCCNC(=O)CCNC(C)=O$

HCID86746429

未命名化合物

结构：Cl.Nc1ccc(N=Nc2ccccc2)c(N)n1.O=[Cr](=O)([O-])Cl

HCID178479088

未命名化合物

PRODUCTS

生成物

$结构：CCCCCCCC/C=C\CCCCCCCC(=O)CCCNC(=O)CCNC(C)=O$

HCID86746428

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

A 160 mg portion of 3-(acetylamino)-N-(4-hydroxy-12(Z)-heneicosenyl)propanamide was dissolved in 5 ml of dichloromethane and treated with 157 mg of pyridium chlorochromate for 2 hours. The solution was passed through a short pad of hydrous magnesium silicate and washed repeatedly with fresh dichloromethane. The filtrate and washes were combined and evaporated, giving 92 mg of the desired product as an off-white solid, mp 123°-125° C.

WORKUP

后处理

washwashed repeatedly with fresh dichloromethane
customevaporated

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-33ad43920a414380bde36a066042e10f
来源数据集: uspto-grants-1992_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05173510
来源说明: uspto-grants-1992_12

反应 SMILES

[C:1]([NH:4][CH2:5][CH2:6][C:7]([NH:9][CH2:10][CH2:11][CH2:12][CH:13]([OH:31])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]/[CH:21]=[CH:22]\[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])=[O:8])(=[O:3])[CH3:2].C1C=CC(N=NC2C=CC(N)=NC=2N)=CC=1.Cl.[Cr](Cl)([O-])(=O)=O.[Si]([O-])([O-])([O-])[O-].[Mg+2].[Mg+2]>ClCCl>[C:1]([NH:4][CH2:5][CH2:6][C:7]([NH:9][CH2:10][CH2:11][CH2:12][C:13](=[O:31])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]/[CH:21]=[CH:22]\[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])=[O:8])(=[O:3])[CH3:2]