HuagongsheHuagongshe Chemistry Print Report · For research reference only
Magnesium orthosilicate → 3-(Acetylamino)-N-(4-oxo-12(Z)-heneicosenyl)propan amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Magnesium orthosilicate | HCID 66225 | — |
| Reactant | 3-(acetylamino)-N-(4-hydroxy-12(Z)-heneicosenyl)propanamide | HCID 86746429 | — |
| Reactant | HCID 178479088 | HCID 178479088 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-(Acetylamino)-N-(4-oxo-12(Z)-heneicosenyl)propan amide | HCID 86746428 | — |
Reaction Steps
A 160 mg portion of 3-(acetylamino)-N-(4-hydroxy-12(Z)-heneicosenyl)propanamide was dissolved in 5 ml of dichloromethane and treated with 157 mg of pyridium chlorochromate for 2 hours. The solution was passed through a short pad of hydrous magnesium silicate and washed repeatedly with fresh dichloromethane. The filtrate and washes were combined and evaporated, giving 92 mg of the desired product as an off-white solid, mp 123°-125° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05173510 |
| Source dataset | uspto-grants-1992_12 |
| ORD ID | ord-33ad43920a414380bde36a066042e10f |
| Source note | uspto-grants-1992_12 |