Ethanol → Sodium ZINC monocetylphosphate

HRID 1681801Notes

Reaction equation

HRID 1681801 reaction equation
[CH2:1]([O:17][P:18](=[O:21])([OH:20])[OH:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].C(O)C.[OH-].[Na+:26].O.O.O.O.O.O.O.S([O-])([O-])(=O)=O.[Zn+2:39]>O>[CH2:1]([O:17][P:18]([O-:21])([O-:20])=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[Zn+2:39].[Na+:26]

Participants

6

Reactant 4

HCID 702EthanolHCID 14798Sodium Hydroxide2×HCID 19059Hexadecyl phosphateHCID 62640Zinc Sulfate Heptahydrate

Product 1

HCID 22244895Sodium ZINC monocetylphosphate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

50 g of monocetylphosphoric acid and 100 g of ethanol were placed in a 500 ml reaction vessel. Further, a solution of 6.29% of 96% sodium hydroxide (purity was taken into consideration by calculating it from the degree of neutralization determined by titration) dissolved in 200 g of ionexchanged water was added thereto. After the temperature was elevated to 80° C., it was confirmed that they were clearly dissolved. The solution was continuously stirred for 30 minutes. A solution of 22.3 g of zinc sulfate heptahydrate dissolved in 100 g of ion-exchanged water was added dropwise thereto to carry out a salt exchange reaction. After the completion of the dropwise addition, the mixture was stirred for 30 minutes. 9.30 g of an aqueous solution of 33.33% sodium hydroxide was added dropwise thereto, to thereby adjust the pH of the reaction mixture to 5. Further, the mixture was stirred for one hour. After the completion of the reaction, the reaction mixture was cooled and the product was recovered by filtration, washed with water and dried, to obtain 51.2 g of the particles of sodium zinc monocetylphosphate.

Workup

  1. additionwas added
  2. customwas elevated to 80° C.
  3. dissolutionwere clearly dissolved
  4. additionwas added dropwise
  5. customa salt exchange reaction
  6. additionAfter the completion of the dropwise addition
  7. stirringthe mixture was stirred for 30 minutes
  8. stirringFurther, the mixture was stirred for one hour
  9. customAfter the completion of the reaction
  10. temperaturethe reaction mixture was cooled
  11. filtrationthe product was recovered by filtration
  12. washwashed with water
  13. customdried

Sources & evidence

ORD record
ord-f0a5490b81874ce9916657ce0ba92790
Source dataset
uspto-grants-1992_12
Patent number
US05174991

Reaction notes

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