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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1681815Generated: October 30, 2026

4-[4-(1-Piperidinyl)butyl]piperidine → 6,11-Dihydro-11-[[4-[4-(1-piperidinyl)butyl]-1-piperidinyl]-acetyl]-5H-pyrido [2,3-b][1,5]benzodiazepin-5-one

https://huagongshe.com/reaction/1681815

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[4-(1-Piperidinyl)butyl]piperidineHCID 14374292—
Reactant11-(chloroacetyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-oneHCID 19804217—
Product6,11-Dihydro-11-[[4-[4-(1-piperidinyl)butyl]-1-piperidinyl]-acetyl]-5H-pyrido [2,3-b][1,5]benzodiazepin-5-oneHCID 1437431237%

Reaction Steps

Prepared analogously to Example 1 from 11-(chloroacetyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one and 4-[4-(1-piperidinyl)butyl]piperidine in a yield of 37% of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05175158
Source datasetuspto-grants-1992_12
ORD IDord-705068ef6f3243ab84ff616088de5342
Source noteuspto-grants-1992_12