Hydrochloric Acid → HCID 70148563, compound

Participants

Reaction Steps

2-Aminopyridine-4-carboxylic acid (Farmaco. Ed. Sci. 1958, 13, 485; 1.38 g, 10 mmol) was dissolved in 90% methanol (210 ml) and conc. HCl(4.9 ml, 60 mmol) was added. The solution was hydrogenated over PtO2 (200 mg) in a Parr shaker apparatus at room temperature and 29 psig for 2 hours. Filtration and evaporation gave 1.57 g (88%) crude white crystals identified as the product by 300 MHz nmr and ir 1728 cm-1.

Provenance & Evidence